Perspective
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Chronobiology of the Tumor Microenvironment: Implications for Therapeutic Strategies and Circadian-Based Interventions
Dengxiong Li, Qingxin Yu, Ruicheng Wu, Zhouting Tuo, Weizhen Zhu, Jie Wang, Fanglin Shao, Luxia Ye, Xing Ye, Koo Han Yoo, Mang Ke, Yubo Yang, Wuran Wei, Dechao Feng
Review
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Amyloid-β and Phosphorylated Tau are the Key Biomarkers and Predictors of Alzheimer’s Disease
Jangampalli Adi Pradeepkiran, Javaria Baig, Md Ariful Islam, Sudhir Kshirsagar, P. Hemachandra Reddy
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Vascular Calcification Heterogeneity from Bench to Bedside: Implications for Manifestations, Pathogenesis, and Treatment Considerations
Kuo-Cheng Lu, Kuo-Chin Hung, Min-Tser Liao, Li-Jane Shih, Chia-Ter Chao
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Drug Screening and Validation Targeting TDP-43 Proteinopathy for Amyotrophic Lateral Sclerosis
Jiaqi Xin, Sen Huang, Jing Wen, Yunhao Li, Ang Li, Senthil Kumaran Satyanarayanan, Xiaoli Yao, Huanxing Su
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Age-Related Dysfunction in Balance: A Comprehensive Review of Causes, Consequences, and Interventions
Jixian Wang, Yongfang Li, Guo-Yuan Yang, Kunlin Jin
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Endogenous Retroviruses Unveiled: A Comprehensive Review of Inflammatory Signaling/Senescence-Related Pathways and Therapeutic Strategies
Xin-ran Zhao, Jia-bin Zong, Yu-xiao Liu, Tuersun Aili, Min Qiu, Jie-hong Wu, Bo Hu
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Assessing the Influence of Maternal Age in Bovine Embryos and Oocytes: A Model for Human Reproductive Aging
Aleksander Franciszek Butkiewicz, Ana Amaral, Marta Cerveira-Pinto, Pawel Kordowitzki
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The Role of Liquid-Liquid Phase Separation in the Accumulation of Pathological Proteins: New Perspectives on the Mechanism of Neurodegenerative Diseases
Xingyu Lu, Jiongtong Lu, Shengnan Li, Sifan Feng, Yan Wang, Lili Cui
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Cell-Free DNA As Peripheral Biomarker of Alzheimer’s Disease
Sachi Khemka, Ujala Sehar, Pulak R Manna, Sudhir Kshirsagar, P. Hemachandra Reddy
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Repurposing Ketamine in the Therapy of Depression and Depression-Related Disorders: Recent Advances and Future Potential
Qianting Deng, Emily Parker, Chongyun Wu, Ling Zhu, Timon Cheng-Yi Liu, Rui Duan, Luodan Yang
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Role of Serotonylation and SERT Posttranslational Modifications in Alzheimer's Disease Pathogenesis
Arubala P. Reddy, Priyanka Rawat, Nicholas Rohr, Razelle Alvir, Jasbir Bisht, Mst Anika Bushra, Jennifer Luong, Aananya P. Reddy
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Inflammatory Markers Associated with Physical Frailty and Cognitive Impairment
Yiming Pan, Lina Ma
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Exosomal Proteomics: Unveiling Novel Insights into Lung Cancer
Guanhua Yi, Haixin Luo, Yalin Zheng, Wenjing Liu, Denian Wang, Yong Zhang
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Skin-brain axis in Alzheimer's disease - Pathologic, diagnostic, and therapeutic implications: A Hypothetical Review
Hyeon soo Kim, Haram Jung, Yong Ho Park, Su-Hak Heo, Sujin Kim, Minho Moon
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Disulfidptosis, A Novel Cell Death Pathway: Molecular Landscape and Therapeutic Implications
Qiuyang Gu, Yumei An, Mingyuan Xu, Xinqi Huang, Xueshi Chen, Xianzhe Li, Haiyan Shan, Mingyang Zhang
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Revolutionizing Diabetic Foot Ulcer Care: The Senotherapeutic Approach
Guiqin Zhang, Priyadarshani Nadeeshika Samarawickrama, Li Gui, Yuan Ma, Mei Cao, Hong Zhu, Wei Li, Honglin Yang, Kecheng Li, Yang Yang, Enfang Zhu, Wen Li, Yonghan He
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Expert Consensus on Prevention and Treatment of Aging-Related Gonadal Dysfunction
Xi Wang, Li Ma, Sheng Jiang, Junping Wen, Zhaoli Yan, Long Tian, Shan Deng, Boxian Huang, Ilia Stambler, Calogero Caruso, Kyung-Jin Min, Huanxing Su, Kunlin Jin, Jiangfeng Mao, Xueyan Wu, Qin Han, Robert Chunhua Zhao
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Aging Gut Microbiome in Healthy and Unhealthy Aging
Yangyanqiu Wang, Zhanbo Qu, Jian Chu, Shuwen Han
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Aging-Related Sarcopenia: Metabolic Characteristics and Therapeutic Strategies
Yonglian Chen, Jinhui Wu
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Navigating the Complex Terrain of Dysregulated Microglial Function in Depressive Disorders: Insights, Challenges and Future Directions
Yuling Zhang, Chaozhi Tang
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Current Understanding of Marginal Grafts in Liver Transplantation
Ze Xiang, Jiarui Li, Huixuan Zeng, Xiaonan Xiang, Fengqiang Gao, Kai Wang, Xuyong Wei, Shusen Zheng, Xiao Xu
Original Article
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Adiponectin mRNA Conjugated with Lipid Nanoparticles Specifically Targets the Pathogenesis of Type 2 Diabetes
Rady E. El-Araby, Qisheng Tu, Ying Xie, Tarek Aboushousha, Zhongyu Li, Xiaoyang Xu, Zoe X. Zhu, Lily Q. Dong, Jake Chen
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m6A Reader HNRNPC Facilitates Adipogenesis by Regulating Cytoskeletal Remodeling through Enhanced Lcp1 mRNA Stability
Wenhua Xie, Yewei Cui, Lingzhi Yue, Ting Zhang, Chenglong Huang, Xinyu Yu, Dan Ma, Dongfang Liu, Rui Cheng, Xueya Zhao, Xi Li
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Progressive Disruption of Sphingosine-1-Phosphate Receptor 1 Correlates with Blood-Brain Barrier Leakage in A Rat Model of Chronic Hypoxic Hypoperfusion
Jeffrey Thompson, Yirong Yang, Kelsey Duval, Michael Griego, Haojie Chen, Karen SantaCruz, Haoran Deng, Carlos Perez, Sean Maez, Sasha Hobson, Theodore Li, Halima Akter, Michel Torbey, Yi Yang
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The NRF2/ID2 Axis in Vascular Smooth Muscle Cells: Novel Insights into the Interplay between Vascular Calcification and Aging
Mulin Xu, Xiuxian Wei, Jinli Wang, Yi Li, Yi Huang, Anying Cheng, Fan He, Le Zhang, Cuntai Zhang, Yu Liu
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Association between Body Iron Status and Cognitive Task Performance in a Nationally Representative Sample of Older Adults
Jianying Peng, Buyun Liu, Wei Tan, Shouzhang Hu, Benchao Li, Jin Zhou, Guifeng Xu, Yangbo Sun, Linda G. Snetselaar, Robert B. Wallace, Shuang Rong, Wei Bao
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Hypermethylation of Bmp2 and Fgfr2 Promoter Regions in Bone Marrow Mesenchymal Stem Cells Leads to Bone Loss in Prematurely Aged Mice
Yao Wang, Lin Sun, Tianyou Kan, Wendong Xue, Han Wang, Ping Xu, Lei Zhang, Mengning Yan, Hanjun Li, Zhifeng Yu
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Inferior Frontal Sulcal Hyperintensity on Fluid-Attenuated Inversion Recovery Is Related to Cerebrospinal Fluid Clearance via Putative Meningeal Lymphatics
Ziyu Zhou, Ying Zhou, Wang Ran, Shenqiang Yan, Xiao Zhu, Zhongyu Luo, Huihong Ke, Kemeng Zhang, Mengmeng Fang, Jianzhong Sun, Min Lou
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Fecal Microbiota Transplantation Attenuates Frailty via Gut-Muscle Axis in Old Mice
Mengpei Zhu, Yumei Huang, Ziwen Wang, Ze Jin, Jiali Cao, Qiangqiang Zhong, Zhifan Xiong
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Nogo-A Drives Alzheimer’s Disease Progression by Inducing Tauopathy Vulnerability
Zijian Wang, Jun-ping Pan, Jiayuan Geng, Shijie Lv, Guisi Chen, Nian Fang, Zheng Zhang, Junliang Li, Xinke Xu, Rui Wang, Qing Zheng, Li Yan, Guobing Chen, Fei Xiao
