Commentary
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CAG Repeat Expansions Increase N1-Methyladenine to Alter TDP-43 Phase Separation: Lights Up Therapeutic Intervention for Neurodegeneration
Lin Yuan, Li-Hong Mao, Jia-Yi Li
Perspective
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A Neglected Gene: The Role of the ANG Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis
Yu Zhang, Yanan Li, Shen Bin, Xi Cheng, Qi Niu
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Vascular Aging and Atherosclerosis: A Perspective on Aging
Shudong Ma, Xuena Xie, Rong Yuan, Qiqi Xin, Yu Miao, Sean Xiao Leng, Keji Chen, Weihong Cong
Review
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Optical Coherence Tomography Angiography: Revolutionizing Clinical Diagnostics and Treatment in Central Nervous System Disease
Zeqi Shen, Sheng Zhang, Weitao Yu, Mengmeng Yue, Chaoyang Hong
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Immunological Landscape of Retinal Ischemia-Reperfusion Injury: Insights into Resident and Peripheral Immune Cell Responses
Shan He, Cuiying Liu, Changhong Ren, Heng Zhao, Xuxiang Zhang
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Fighting with Aging: The Secret for Keeping Health and Longevity of Naked Mole Rats
Wenjing Yang, Yifan Hu, Shufang Cui
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Role and Mechanism of Epigenetic Regulation in the Aging of Germ Cells: Prospects for Targeted Interventions
Xiang-Chun Huang, Yi-Nan Jiang, Hai-Juan Bao, Jie-Lin Wang, Rong-Jin Lin, Jing Yuan, Jing-Yuan Xian, Yang Zhao, Shuo Chen
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Nanomaterials in Medicine: Understanding Cellular Uptake, Localization, and Retention for Enhanced Disease Diagnosis and Therapy
Yue Peng, Zhengshuang Yang, Hui Sun, Jinling Li, Xiuwan Lan, Sijia Liu
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Inflammatory Pathogenesis of Post-stroke Depression
Xinyu Feng, Xiaojuan Ma, Juan Li, Qing Zhou, Yao Liu, Jingyi Song, Jiaqi Liu, Qingqing Situ, Lingyue Wang, Jingzhi Zhang, Facai Lin
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Emerging Roles of UDP-GalNAc Polypeptide N-Acetylgalactosaminyltransferases in Cardiovascular Disease
Liwei Guo, Lulu Zhou, Pengcheng Wei, Shijie Li, Shanqing He, Duan Li
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ROS-Induced Endothelial Dysfunction in the Pathogenesis of Atherosclerosis
Ruiyi Yan, Xiao Zhang, Wenlong Xu, Jiayao Li, Yixin Sun, Shengyan Cui, Ran Xu, Wenjing Li, Liqun Jiao, Tao Wang
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YAP/TAZ as Molecular Targets in Skeletal Muscle Atrophy and Osteoporosis
Youngjoo Kwon
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Senescent T Cells in Age-Related Diseases
Pei-Jie Yu, Mei Zhou, Yan Liu, Jie Du
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Scoping Review of Technological Solutions for Community Dwelling Older Adults and Implications for Instrumental Activities of Daily Living
Umut Arioz, Urška Smrke, Nejc Plohl, Tanja Špes, Bojan Musil, Izidor Mlakar
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The Role of p53 in Regulating Chronic Inflammation and PANoptosis in Diabetic Wounds
Wenjie He, Ming Tang, Rifang Gu, Xingqian Wu, Xinrui Mu, Xuqiang Nie
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Neuroinflammation and Post-Stroke Depression: Focus on the Microglia and Astrocytes
Weizhuo Lu, Jiyue Wen
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Over-the-Counter Anti-inflammatory Supplements for Adjunctive Rheumatoid Arthritis Therapy: A Comprehensive Narrative Review
Saliba Fares, Mourad Omar, Aoun Laurence, Saif Abu-Baker, Almardini Shaza, Haddadin Fadi, Mina Jonathan, Khattar Georges, Sangaraju Koushik, Bou Sanayeh Elie, Morcos Zeina, Habib Toni, Al Saidi Ibrahim, Slobodnick Anastasia
Original Article
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A Dual-Task Paradigm Combining Physical and Cognitive Training in Mice: Application to Aging
Elpidio Attoh-Mensah, Antoine Huret, Marianne Leger, Gilles Loggia, Gerald Nee, Stacy Largilliere, Daniel Zuba, Chantal Chavoix, Pascale Schumann-Bard, Thomas Freret
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Inhibiting Glutaminase Exerts Opposite Effects on Ovariectomy-Induced and Age-Related Reductions in Murine Bone Mass
Qian Guo, Hongjian Zhao, Zijian Dong, Haozhe Cheng, Meipeng Zhu, Zhong Fang
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Lipid Droplets Accumulation in the Brain of HIV Transgenic Rat: Implication in the Accelerated Aging of HIV Infected Individuals
Ming-Lei Guo, Yan Cheng, Damian Martinez Pineda, Rachael E. Dempsey, Lifang Yang
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Orthostatic Hypotension and Cognitive Function in Individuals 85 Years of Age: A Longitudinal Cohort Study in Sweden
Peder af Geijerstam, Katie Harris, Maria M. Johansson, John Chalmers, Katarina Nägga, Karin Rådholm
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Targeting Estrogen Receptor Beta Ameliorates Diminished Ovarian Reserve via Suppression of the FOXO3a/Autophagy Pathway
Fangyuan Li, Jingwen Zhu, Jinchen Liu, Yongyan Hu, Peili Wu, Cheng Zeng, Ruihui Lu, Ning Wu, Qing Xue
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Elevated CD4+ T Cell Senescence Associates with Impaired Immune Responsiveness in Severe COVID-19
Jie Zhang, Chun Chang, Zhaoyuan Liang, Tingting Hu, Zhongnan Yin, Ying Liang, Ting Zhang, Yanling Ding, Xianlong Li, Xiaoyan Gai, Xiaoxue Yang, Xin Li, Xixuan Dong, Jiaqi Ren, Yafei Rao, Jun Wang, Jianling Yang, Lixiang Xue, Yongchang Sun
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Mortality Outcomes in a Large Population with and without Covert Cerebrovascular Disease
Úna Clancy, Eric J. Puttock, Wansu Chen, William Whiteley, Ellen M. Vickery, Lester Y. Leung, Patrick H. Luetmer, David F. Kallmes, Sunyang Fu, Chengyi Zheng, Hongfang Liu, David M. Kent
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Neuron Derived Cold-Inducible RNA-Binding Protein Promotes NETs Formation to Exacerbate Brain Endothelial Barrier Disruption after Ischemic Stroke
Zhifang Li, Shuai Sun, Qinghui Xiao, Senwei Tan, Huijuan Jin, Bo Hu
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DNA Demethylation of Promoter Region Facilitates Atoh-1-Induced Interleukin-19 Expression Activation in Bone Marrow Monocytes of Old Mice
Yanan Chen, Longshuai Lin, Shengzhe Ruan, Jianxin Ye, Zhicheng Dai, Guangzhen Mao, Yongming Xi, Changping Wang, Qinghua Zhao
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Choroid Plexus Volume, Amyloid Burden, and Cognition in the Alzheimer’s Disease Continuum
Seong Ho Jeong, Chae Jung Park, Jungho Cha, Sang-Young Kim, Seung-Koo Lee, Yun Joong Kim, Young H. Sohn, Seok Jong Chung, Phil Hyu Lee
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Machine Learning-Based Decision-Making in Geriatrics: Aging Phenotype Calculator and Survival Prognosis
Aleksandra Mamchur, Natalia Sharashkina, Veronika Erema, Daria Kashtanova, Mikhail Ivanov, Maria Bruttan, Elena Zelenova, Eva Shelly, Valentina Ostapenko, Irina Dzhumaniiazova, Lorena Matkava, Vladimir Yudin, Anna Akopyan, Irina Strazhesko, Lilit Maytesyan, Irina Tarasova, Olga Beloshevskaya, Anton Keskinov, Sergey Kraevoy, Olga Tkacheva, Sergey Yudin
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Neuronal Intranuclear Inclusion Disease with NOTCH2NLC GGC Repeat Expansion: A Systematic Review and Challenges of Phenotypic Characterization
Tian Zeng, Yiqun Chen, Honghao Huang, Shengqi Li, Jiaqi Huang, Haobo Xie, Shenyi Lin, Siyao Chen, Guangyong Chen, Dehao Yang
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MKK3 K329 Mutation Attenuates Diabetes-Associated Cognitive Dysfunction by Blocking the MKK3-RAGE Interaction and Inhibiting Neuroinflammation
Changjiang Ying, Yan Li, Shidi Wu, Lin Gao, Yandong Zhu, Ye Qian, Xiangru Wen, Hui Li, Chengyu Huang, Bin Hu, Yuanjian Song, Xiaoyan Zhou
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Neuroanatomical Signature of the Transition from Normal Cognition to MCI in Parkinson's Disease
Iman Beheshti, Jarrad Perron, Ji Hyun Ko
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Osteoporosis in Relation to a Bone-Related Aging Biomarker Derived from the Urinary Proteomic Profile: A Population Study
Yu-Ling Yu, Dries S. Martens, De-Wei An, Babangida Chori, Agnieszka Latosinska, Justyna Siwy, Augustine N. Odili, Katarzyna Stolarz-Skrzypek, Gladys E. Maestre, Kei Asayama, Yan Li, Peter Verhamme, Karel Allegaert, Harald Mischak, Tim S. Nawrot, Jan A. Staessen
