Impaired Frontoparietal Connectivity in Traumatic Individuals with Disorders of Consciousness: A Dynamic Brain Network Analysis

Wu Min, Li Fali, Wu Yuehao, Zhang Tieying, Gao Jian, Xu Peng, Luo Benyan

Table 1 The characteristic data of patients in DOC.

Patient clinical diagnosis gender/age etiology Lesions (CT or MRI) Month since injury CRS-R sub-scores CRS-R total scores 01 MCS M/40 Trauma Bilateral frontal, temporal and right parietal, occipital lobe lesions 7.1 1 0 3 0 0 2 6 02 MCS M/67 Hemorrhage Bilateral frontal, temporal lobe lesions 3.0 0 0 3 0 0 2 5 03 MCS F/72 Hemorrhage Right frontal, temporal lobe, basal ganglia and brain stem lesions 6.1 1 1 3 0 0 2 7 04 MCS M/70 Trauma Bilateral frontal, temporal lobe lesions 2.2 0 1 4 0 0 2 7 05 MCS F/44 Anoxia Diffuse demyelination 3.1 2 3 1 1 0 2 9 06 MCS M/31 Hemorrhage Brain stem lesions 10.8 1 2 3 0 0 2 8 07 MCS M/73 Hemorrhage Brain stem and cerebellum lesions 4.0 2 3 4 0 0 3 12 08 MCS M/43 Trauma Left temporal, parietal lobe lesions 3.2 1 2 3 0 0 2 8 09 MCS F/67 Trauma Bilateral frontal lobe and left parietal lobe lesions 2.5 1 0 2 1 0 2 6 10 MCS F/68 Hemorrhage Left basal ganglia lesions 2.2 2 2 3 0 0 3 10 11 MCS M/60 Hemorrhage SAH 2.2 4 4 5 2 1 3 19 12 MCS M/61 Hemorrhage Right basal ganglia lesions 2.5 2 3 2 0 0 2 9 13 MCS M/45 Trauma Bilateral frontal lobe and left parietal lobe lesions 2.7 2 3 2 0 0 2 9 14 MCS F/48 Trauma Bilateral frontal lobe and left parietal lobe lesions 6.3 2 2 3 0 0 2 9 15 VS M/44 Anoxia Diffuse demyelination 7.3 1 0 1 0 0 2 4 16 VS M/42 Anoxia Diffuse demyelination 7.1 0 0 1 1 0 2 4 17 VS M/65 Trauma Left frontal and parietal lobe lesions 3.0 0 1 0 0 0 2 3 18 VS M/34 Hemorrhage Right temporal, parietal and occipital lobe and left frontal lobe lesions 0.7 0 0 1 0 0 2 3 19 VS F/26 Trauma Bilateral frontal and temporal lesions 2.1 2 1 2 0 0 2 7 20 VS M/33 Trauma Diffuse demyelination 6.1 0 0 1 0 0 2 3 21 VS M/59 Trauma Left frontal and temporal lobe, basal ganglia lesions 2.2 0 1 1 0 0 2 4 22 VS M/62 Trauma Right frontal and temporal lobe lesions 4.4 0 0 2 0 0 2 4 23 VS M/52 Trauma SAH, right temporal lobe lesions 2.5 1 1 2 0 0 2 6 24 VS F/55 Hemorrhage left frontal and temporal lesion 1.6 1 1 2 0 0 2 6 25 VS M/35 Hemorrhage Brain stem lesion 6.0 0 0 2 0 0 2 4 26 VS F/49 Hemorrhage Brain stem lesion 3.2 0 0 2 0 0 2 4 27 VS M/54 Trauma SAH 1.7 2 1 2 0 0 2 7 28 VS F/67 Trauma Right temporal lobe lesions 5.9 0 1 1 0 0 2 4 29 VS F/53 Hemorrhage SAH 1.4 2 1 2 0 0 3 8 30 VS M/69 Hemorrhage Brain stem lesion 2.0 0 1 2 1 0 2 6 31 VS F/63 Trauma Right temporal lobe lesions 4.0 0 1 2 0 0 2 5 32 VS M/75 Trauma Left frontal and temporal lobe lesions 2.4 2 1 2 2 0 2 9