T1-weighted MRI-driven Brain Age Estimation in Alzheimer’s Disease and Parkinson’s Disease

Beheshti Iman, Mishra Shiwangi, Sone Daichi, Khanna Pritee, Matsuda Hiroshi

Table 4 Partial correlation (r) of WM Brain-EAD values with clinical parameters among PD patients with adjustment for age and sex (n = 160).

Variable r p-value Variable r p-value Duration of disease -0.06 0.19 S&E -0.12 0.05 MoCA -0.15 0.04 UPSIT - Total Score -0.14 0.04 GDS -0.13 0.43 SCOPA-AUT 0.02 0.42 MDS-UPDRS Total 0.06 0.23 SBR-Left Caudate 0.01 0.48 MDS-UPDRS Part I 0.21 0.005 SBR-Right Caudate -0.04 0.27 MDS-UPDRS Part I Patient Questionnaire 0.02 0.42 SBR-Left Putamen 0.02 0.39 MDS-UPDRS Part II Patient Questionnaire -0.02 0.40 SBR-Right Putamen -0.12 0.06 MDS-UPDRS Part III 0.06 0.06